The weight loss difference between liraglutide and phentermine is smaller than with semaglutide or tirzepatide, which means the other factors, cost, side effects, duration of treatment, and long-term outcomes, carry more relative weight in the decision
Compared with group C, the levels of PO 2 and Cl were increased in group D, and the difference was statistically significant
But it's like finding a clue in a mystery - it makes us want to look for more
NICE guidance (NG28) recommends GLP-1 receptor agonists as a treatment option for adults with type 2 diabetes when: Triple therapy with metformin and two other oral drugs is not effective, not tolerated or contraindicated The person has a BMI of 35 kg/m or higher (adjust accordingly for people from particular ethnic groups) and specific psychological or other medical problems associated with obesity The person has a BMI lower than 35 kg/m and insulin would have significant occupational implications, or weight loss would benefit other significant obesity-related comorbidities GLP-1 receptor agonists may also be considered in combination with insulin therapy in specialist care settings Beyond glycaemic control, specific GLP-1 receptor agonists offer significant cardiovascular benefits
Yang J, Zhang X, Zhang Y, et al
berberine is a food supplement regulated under UK food law