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In addition to protein, antioxidants are also vital for glutathione synthesis

Effect of intraocular sustained release of indomethacin on postoperative inflammation and posterior capsule opacification

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proposed that methylation of HTM-directed H3K9 sites must have DNMT3b-dependent DNA methylation processes at centromeric repeats, indicating that epigenetic histone methylation and DNA methylation regulate each other in balance (Pal and Tyler, 2016)