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A new study presented at ENDO 2025 , the annual meeting of the Endocrine Society held in San Francisco, provides compelling evidence that anti-obesity medications may offer an effective intervention

Note that the documented GLOW protocol holds the per-dose size constant

Behavioral support enhances adherence and lifestyle integration for many patients, but medication efficacy does not depend on it

PMID:17392149

Increase when all of these conditions are true: your GI symptoms at the current dose have resolved or become minimal, you are not experiencing persistent nausea or vomiting, you feel comfortable with the current level of appetite suppression, and your provider has approved the increase