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Incretin-based therapies for the treatment of non-alcoholic fatty liver disease: a systematic review and meta-analysis
The lack of regulation and limited clinical research further complicate the picture, leaving much about its safety uncertain
FIGURE 1 Mitochondrial dysfunction and oxidative species Cholestasis is characterized by the induction of oxidative stress and a dysfunctional mitochondrial architecture ( Patients with cholestatic disease frequently present increased expression of mitochondrial methylation-controlled J-protein (MCJ), which inhibits electron transport chain complex I
doi:10.1016/0014-5793(88)80509-x
Research regarding their medical effects is extensive
When transitioning between them , matching the appropriate dose level prevents both under-treatment and excessive side effects during the changeover period
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