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MDSC blockade would likely diminish the secretion of anti-inflammatory cytokines such as prostaglandin E2 and nitric oxide, which are known to inhibit NK cell cytotoxicity

In organisms, two systems have been developed to neutralize these compounds, including non-enzymatic and enzymatic systems

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Evaluation of ischemia-reperfusion injury by malondialdehyde, glutathione and gamma-glutamyl transpeptidase: lack of specific local effects in diverse parts of the dog heart following acute coronary occlusion