The effects of this presentation on weight and glycemia in clinical trials and real-world settings are comparable to those induced by the subcutaneous presentation, although a specific indication for weight control without DT2 is still lacking.86 In order to avoid confusion in daily clinical practice, it is important to note that liraglutide 3mg and semaglutide 2.4mg can be used in patients with DT2, provided these are obese or overweight with comorbidities
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These findings highlight the critical role of GLP-1 analogues in modulating immune responses within atherosclerotic lesions, supporting their potential to reduce cardiovascular risk beyond their effects on glycaemic control (Table 1
However, genetic testing informs dose optimization within the standard weekly frameworkit never justifies more frequent injections, as the once-weekly schedule remains medically necessary
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Chia seeds and flaxseeds excellent sources of soluble fiber that forms a gel in the gut, slowing digestion and extending nutrient contact with L-cells