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Mechanically, GLP-1RAs regulate insulin-like growth factor-1/2 and upregulate -estrogen receptors to exert cardioprotective actions in isoprenaline-induced MI [73]

doi: 10.3389/fphar.2025.1656217 Received 29 June 2025 Accepted 29 September 2025 Published 20 October 2025 Volume 16 - 2025 Edited by Zou Jian, Jinan University, China Reviewed by Zhi Jiang, The Second Affiliated Hospital of Guanghzou University of Chinese Medicine, China Hee Geun Jo, Gachon University, Republic of Korea Updates Copyright 2025 Hong and Xiao

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This notion was supported by the demonstration that -VLDLs isolated from KO rabbits were cleared faster from the circulation than those of WT rabbits