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However, chronic inhibition or ablation of ARC AgRP/NPY neurons or chronic activation of ARC POMC neurons fails to affect body weight in a stable manner [139,140,141,142]

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The new study addresses this void

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Control-A bottles were filled with the oxygen-saturated model wine solution without adding any antioxidant, and Control-B bottles were filled with the same model wine solution, but after bubbling for 10 min with nitrogen to eliminate the oxygen

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Peer review Peer review information Nature thanks Lucas Sullivan and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

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Why does semaglutide carry a thyroid tumour warning

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