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However, while B12 injections or oral supplements are typically considered safe, there are significant risks when administered without proper preliminary testing

Obstructive sleep apnea severity reduces

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For most patients, B12 injections do not cause any significant long-term health concerns

Patients with malabsorption syndromes or post-bariatric surgery

One study found that after injecting high doses of vitamin B12 (specifically cyanocobalamin) into rodents, the B12 stayed in the bloodstream for a relatively short period, with a half-life ranging from 20 to 50 minutes