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The proposed pathway is restoration of pinealocyte function either by direct gene-regulatory effects on serotonin-N-acetyltransferase (AANAT) and related enzymes, or indirectly by reducing neuroendocrine stress signalling
For comparison, the average bariatric surgery patient loses about 25-to-35% of their body weight
Research Center for Drug Evaluation
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Traditionally, clinicians have associated MASLD with obesity, insulin resistance, and type 2 diabetes, often using body mass index (BMI) and A1C as screening triggers
912 November 2025, San Antonio, TX
