However, careful consideration must be given to the safety profile of GLP-1 RAs, particularly their gastrointestinal side effects and rare risks, such as pancreatitis and thyroid-related complications [19, 71]
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Tirzepatide takes this a step further by also activating GIP receptors, making it a dual-action injectable that targets hunger from two hormonal pathways simultaneously
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Systematic reviews of clinical trial data do not identify myalgia as occurring at significantly higher rates in GLP-1-treated patients compared to placebo groups