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It raises an important question for our field: Are we fully accounting for physiological side effects when individualizing antidepressant therapy or are prescribing decisions still guided primarily by mood response and tolerability

Advancing to the next dose tier becomes appropriate when weight loss plateaus, side effects fully resolve, or your clinician determines that increased potency aligns with your goals

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| Hubmed - HubMedEd, accessed April 23, 2025, Switching From Semaglutide To Tirzepatide: A Comprehensive Guide - Mochi Health, accessed April 23, 2025, Switching From Semaglutide To Tirzepatide Guide In 2025 - Line eraser MD, accessed April 23, 2025, Tirzepatide vs