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Holmgren G, Wikstrom L, Lundgren HE, Suhr OB

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Induces G2/M cell cycle arrest by inducing thiol oxidative stress resulting in -tubulin S-glutathionylation-mediated microtubule depolymerization

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Lipid peroxidation occurs when ROS attack polyunsaturated fatty acids in cell membranes, forming MDA and 4-HNE as toxic byproducts

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