Notably, derivatives bearing L-sugar configurations outperformed their D-sugar counterparts, for instance, 3-O-(2,3,4-tri-O-acetyl--L-glucopyranosyl)-caudatin (Figure 1g) exhibited the highest activity against HepG2 cells (IC 50 3.11 M) (Li X
doi:10.1055/s-0038-1654716 Cannegieter SC
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Its ability to influence gene expression related to these pathways underpins its potential therapeutic role within functional medicine frameworks aimed at reducing oxidative stress and promoting healthy aging.
Epigenetic regulation of the Warburg effect by H2B monoubiquitination