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Int J Sci Res Methodol
Current guidelines from the American Diabetes Association and European Association for the Study of Diabetes recommend combination SGLT-2 inhibitor plus GLP-1 RA therapy for patients with T2DM and established cardiovascular disease or high cardiovascular risk, based on additive cardiorenal benefits [20,21,22,23]
As insulin resistance decreases, these hypertension-promoting pathways shut down, and blood pressure naturally normalizes
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