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It does not have FDA approval for any specific indication

The R -gene mediated, hypersensitive-type resistance (HR, incompatible interaction) is based on a specific interaction, either directly or indirectly, of a bacterial effector gene product with the R gene of the host plant

The elevated concentration provides enhanced therapeutic effects through increased growth factor expression, accelerated angiogenesis, and more robust anti-inflammatory action

Antiapoptotic proteins, such as an inhibitor of apoptosis 2 (IAP-2), could be induced whereas the proapoptotic protein Bax could be downregulated in an HIF-1-dependent manner [86]

By improving blood supply to damaged tissue, the peptide helps deliver oxygen, nutrients, and healing factors that would otherwise struggle to reach poorly vascularized structures like the plantar fascia