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This knowledge now opens novel ways to improve interventions that could combat age-related muscle atrophy and impaired regeneration with fibrosis and fat infiltration (including sarcopenia and frailty)
The glutathione redox ratio (GSH: GSSG) is an indicator of overall glutathione status and intracellular reducing environment
2018;118:709-718.[DOI] 114
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In contrast, Nrf2 activators, such as sulforaphane, have been found to prevent homocysteine- or hydrogen peroxide-induced cataract formation in human lens epithelial cells by increasing nuclear translocation of Nrf2 and expressions of cellular antioxidants, including catalase, superoxide dismutase, glutathione peroxidase, and glutathione
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