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Caroline Apovian, co-director of the Center for Weight Management and Wellness at Brigham and Womens Hospital in Boston
Early research suggests retatrutide may produce the greatest average weight loss, but it is still being studied in clinical trials
She estimates 30 to 40% of them are microdosing either tirzepatide or semaglutide
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If the MVR becomes more severe, with more blood flowing the wrong way, the heart must work harder to pump sufficient oxygenated blood around the body and the upper chamber of the heart can become dilated due to increased pressure
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