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Since MTHFR controls the detoxification of homocysteine and the supply of methyl groups for SAM synthesis, a reduction in its activity can affect homocysteine metabolism and disturb cellular methylation processes

MPGES-1 catalyzes the terminal step of prostaglandin E 2 synthesis through a GSH-dependent isomerization reaction 22

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Heres a breakdown: Signal Transmission Peptides act as messengers

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