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Experimental evidence suggests that the transport of long chain fatty acids into the mitochondria is a rate limiting step in fatty acid oxidation

Theres also a practical challenge: Health insurers dont typically cover obesity medications, says Scott Kahan, an obesity doctor and professor at Johns Hopkins Bloomberg School of Public Health and the George Washington University School of Medicine

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Pathophysiologic approach to therapy in patients with newly diagnosed type 2 diabetes

and Mandrika et al