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Hydroxocobalamin is the first drug of choice for high-dose initial therapy

Image credit: KaterynaBorodina/Shutterstock.com Obesity treatment has been revolutionized by the introduction of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) like semaglutide, and dual GLP-1 RA/glucose-dependent insulinotropic polypeptide [GIP] receptor agonists like tirzepatide

In that case, to truly shift skin tone, you may need a holistic plan, such as laser/light radiation therapies or chemical peels combined with topical actives, like niacinamide, vitamin C, retinoids, etc

A study on the National Institutes of Health website says IV Vitamin B12 administration can be effective for quick correction

Any mention of SUBCUTANEOUS administration