GLUTATHIONE REDOX CYCLE Hydrogen peroxide is rapidly reduced to water mostly by Gpx, which utilizes the reducing equivalents from its substrate GSH
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Rahmouni K, Morgan DA
J Clin Exp Hepatol 3(1):1218 Lavine JE, Schwimmer JB, Van Natta ML, Molleston JP, Murray KF, Rosenthal P, Abrams SH, Scheimann AO, Sanyal AJ, Chalasani N, Tonascia J, nalp A, Clark JM, Brunt EM, Kleiner DE, Hoofnagle JH, Robuck PR (2011) Effect of vitamin E or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents: the TONIC randomized controlled trial
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Comparing the two relies on separate studies with different designs, endpoints, and eras a structurally weaker basis than a single controlled comparison