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Careful medical record documentation of weight loss, health problems and improvements

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However, active GLP-1 is rapidly degraded by dipeptidyl peptidase IV, resulting in a remarkably short plasma half-life of approximately 2 min, with only 1015% of the active hormone remaining in circulation [47]

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It also raises questions as to what the most appropriate incretin to use with type 1 is

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pp 7485 Hayashi E, Maeda T, Tomita T

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