In 14 patients with coronary artery disease and good LV function, intravenous GLP-1 infusion improved global and regional wall LV function on dobutamine stress echocardiography compared with control [92]
Timeline: What to Expect Weeks 14 Adaptation Appetite suppression begins within 4872 hours Early signals Reduced snacking, flatter glucose curves, 24 lb loss (some water/glycogen) Side effects Mild nausea possible
In the gastrointestinal tract, GLP-1 binding to its receptors delays gastric emptying, reduce appetite, and increase satiety [11]
References Wilhelmi de Toledo F, Grundler F, Bergouignan A, Drinda S, Michalsen A
Lyophilized (freeze-dried) formulation supports stability and extended shelf life