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Pocketflow is a data-and-knowledge-driven structure-based molecular generative model

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In response to such stress, Nuclear factor erythroid 2-related factor 2 (NRF2) acts as a key transcription factor, coordinating multiple intracellular antioxidant defense systems by directly or indirectly regulating the expression of downstream target genes such as GPX4, thereby safeguarding cells from ferroptosis

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In its press release, the company says it plans to offer the drug broadly at retail pharmacies and telehealth providers

doi: 10.1016/j.bbr.2016.10.033 207 BombaMCiavardelliDSilvestriECanzonieroLMLattanzioRChiappiniPet al