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Future research endeavors should prioritize identifying the variables responsible for heterogeneity in meta-regression analyses, including factors such as gender, drug dosage, and study duration, which can impact changes in HbA1c and weight

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Participants in Retatrutide trials described their experience not simply as reduced appetite but as genuine disinterest in food

These side effects are more common when starting treatment or after increasing the dose

Improving nutrition before starting GLP-1 medications can provide positive benefits including: Diabetes management Weight management Sleep quality Improved quality of life If lifestyle changes are successful, you may not need to use these medications

doi: 10.3389/fimmu.2024.1370800