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Stockwell and co-workers found that depletion of GSH by erastin inactivated GPX enzymes and induced ferroptosis [21]

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Thus, cellular cysteine and its derivative GSH cooperate to regulate mTORC1 pathway, the ISR and ferroptosis

The cytoplasmic area was defined as a ring region with a width of 1.9 m and a distance of 3.3 m from the nuclear outline

So, for example, during expression and purification of a recombinant protein, it may have a disulfide bond form, which wouldnt normally form in the proteins natural context