semaglutide trizepatide Tirzepatide Linked to Better CV Outcomes Than Tirzepatide as Compared with Semaglutide

Crofford, Implications of glucocorticoid therapy in idiopathic inflammatory myopathies, Nat

Because GLP-1 medications suppress appetite, there's a higher risk of nutrient gaps

Common side effects include nausea, vomiting, diarrhea, and abdominal discomfort

The decision to use GLP-1 receptor agonists should be based on their licensed indications (diabetes or obesity management) rather than cholesterol lowering alone, with lipid improvements considered a beneficial additional effect within a comprehensive cardiovascular risk reduction strategy

Increased expression of the FMO3 gene could be a culprit in atherosclerosis and CVD.8 FMO3 may have adverse effects on blood lipids and glucose independently of TMAO formation, although more research is needed.15 Also, in the liver, trimethyllysine (TML), a modified amino acid, can be converted to GBB and then to carnitine and potentially to TMA and TMAO

The barrier to entry is much lower than it once was. Clearly, peptides have entered the mainstream