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Defined by the amino acid sequence Gly-His-Lys, GHK-Cu coordinates a single copper(II) ion through the nitrogen atoms of the glycine amino terminus, the histidine imidazole ring, and the deprotonated amide nitrogen between residues 1 and 2

Biophysical Chem (2006) 119:618

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In research, it functions as a signal peptide associated with collagen synthesis, fibroblast activation, antioxidant signaling, and broad gene modulation

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