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3.2.2.2 DNA damage Peroxynitrite causes oxidative and nitrative DNA damage: Guanine nitration leads to mutations and strand breaks
Oral Dosing Runs Higher Injectable: 200 to 500mcg per dose Oral: 500 to 1,000mcg per dose, once or twice daily, taken on an empty stomach Higher oral doses are used to make up for the fact that the gut absorbs the compound poorly compared to injections
The incremental benefit over 10mg is measurable but more modest
Its often triggered by a bacterial infection, such as strep throat
Both require a prescription and follow similar titration principles
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