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GLP-1 receptors are distributed throughout the central nervous system, including brain regions involved in pain processing and blood vessel regulation

In addition, a recent study indicates that close to 530 million adult population suffers from diabetes globally

This stability makes both oral and injectable administration viable, though injectable remains the most studied approach

OBrien, N.L

This perspective aligns with emerging interest in exercise-mimetic and immunometabolic therapies that target network-level adaptations rather than single molecular nodes

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