In B cells, ROS are instrumental in regulating activation 31,32 , but the contribution to B cell subsets and functions of mitochondrial ROS (mtROS), which are generated principally within mitochondria, is poorly understood
For experiments with BMDMs from Csf2rb fl/fl Ccr2 -Cre ER T2 and Csf2rb +/+ Ccr2 -Cre ER T2 control mice, 4-hydroxytamoxifen was given at a final concentration of 2 M in full medium for the duration of the differentiation
zaslan MS et al
S.BartenschlagerR
The goal of maintenance therapy is to sustain normal Vitamin B12 levels, as clinical guidelines say
Liu J, Gao M, He J, Wu K, Lin S, Jin L, et al