2026 Europe PMC A cross-species atlas of the dorsal vagal complex reveals neural mediators of the effects of cagrilintide on energy balance
Its targeted mechanism of action makes it a valuable compound for investigating how NNMT inhibition influences metabolic health, mitochondrial function, and longevity-associated biological processes
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Through coordinated GLP-1R and GIPR activation, tirzepatide enhances glucose-dependent insulin secretion, improves glycemic control, contributes to lipid homeostasis, and reduces appetite and food intake, supporting its clinical use in obesity and type 2 diabetes [13]
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It contributes to the renewal of vitamin C and E within cells