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Harding CM, Hennon SW, Feldman MF

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Use evidence-based choices: select peptides with specific mechanisms aligned to the suspected cause rather than broad, undefined mixes

3.1 Syndromes caused by mtDNA and nDNA point mutations 3.1.1 Leigh syndrome Leigh syndrome (LS) is a rare inherited neurological disorder that primarily affects infants and young children, caused by mutations in more than 75 genes of both mitochondrial and nuclear DNA (Lee et al., 2020)