Key points: In the only head-to-head trial, Wegovy produced 15.8% weight loss compared with 6.4% for Saxenda over the same 68-week period Wegovy 7.2 mg (approved January 2026) produces even greater results at 20.7% average weight loss Real-world data from Second Nature shows 19.1% weight loss with semaglutide when combined with behavioural support Semaglutide participants were nearly three times more likely to achieve at least 10% weight loss than liraglutide participants Side effects and tolerability Both medications share a similar side-effect profile, predominantly affecting the gastrointestinal tract
Annals of Dermatology
Phases 2 and 3 No timescale has yet been set for Phase 2 or 3 implementation across Scotland, which will allow prescribing in those with BMI 35 kg/m 2 (32 kg/m 2 in ethnic groups) and BMI 30 kg/m 2 (27 kg/m 2 in ethnic groups), respectively, alongside one or more obesity-related clinical condition
Stay well hydrated, and avoid using NSAIDs during episodes of significant nausea or vomiting where youre struggling to keep fluids down
Skyler J.S., Bergenstal R., Bonow R.O., et al
If you ever need real-time support, like help with side effects, you can always request another on-demand video visit
