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It acts by reoxidising protein disulfide isomerase (PDI), the enzyme catalyzing disulfide formation

Grapes are a source of polyphenols, proanthocyanidins, and resveratrol, all of which modulate oxidative stress and have been studied in a wide range of health conditions, including high blood pressure, cancer, and Alzheimer disease (Pasinetti 2014

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But many times, theyre triggered by outside sources like: Sun exposure (UV radiation) Air pollution Cigarette smoke Toxins and chemicals Stress and poor diet An overload of free radicals sets off something called oxidative stress

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