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It may be related to decreased collagen turnover and reduced production of the precursor proteins from which GHK is naturally released
Pre-clinical work also shows GHK-Cu reducing markers of oxidative stress and inflammatory cytokines in tissue-injury models
Ann Rheum Dis (2013) 72(1):1107
References: DSIP
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Results Methotrexate was found to cause hepatoxicity, as evidenced by an increase in serum levels of liver biomarkers (Fig
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