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Gpx4 uses GSH as cofactor and is needed to prevent lipid peroxidation, which depends on ROS

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doi: 10.1111/J.1365-2249.2008.03713.X 177 CzerneckiTTargoskiZ

Thats especially the case for those containing hydroquinone, which you can read more about here

I was intrigued when I came across a study of people with Down syndrome (who are known to have thyroid issues as they age), that suggested folate supplements helped with preventing thyroid issues

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