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The DUOX1 and DUOX2 members of the NADPH oxidase family are involved in the generation of the the thyroid hormones
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There is also an upside to allowing legitimate compounding
CHAC1 degrades GSH, reducing the GSH/GSSG ratio and impairing the activity of GPX4, an enzyme essential for detoxifying lipid peroxides
Further, the liver is reported to be one of the largest producers of GSH 29
