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Angle the needle against the inside wall of the vial and depress the plunger slowly

[4] The most frequently reported adverse effects include transient gastrointestinal discomfort-nausea, vomiting, abdominal cramps, or diarrhea-particularly when large doses are delivered rapidly

VLP-S2 reduced viral replication in respiratory tissues in hamsters challenged with SARS-CoV-2 Beta, Delta, and Omicron BA.1 variants and against a pangolin coronavirus [164]