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The three activities of OGDH complex are identified as oxoglutarate dehydrogenase (E1o), dihydrolipoamide S-succinyltransferase (DLST or E2o), and dihydrolipoamide dehydrogenase (DLD or E3)

Severe caloric restriction triggers metabolic adaptation (reduced resting metabolic rate), muscle loss, and nutritional deficiencies that can undermine sustained weight loss

Methotrexate for psoriatic arthritis involves a once-a-week dose, either orally or by injection

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6 Deficiencies and prospects of current research Current Omega-3 interventions for ADHD, ASD, TS, and epilepsy show promising yet limited therapeutic effects, constrained by variable individual responses, modest effect sizes, and incomplete mechanistic understanding

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