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Often used to treat hyperpigmentation and ageing concerns, glycolic acid benefits for skin are more visible in people with sensitive and dry skin types
However, these effects, observed at a very early disease stage, probably by affecting autoimmunity, may not be so prominent and of substantial advantage in the advanced stages of GD when symptoms are present and first-line therapy might be applicable
& Thomas, D
Methylcobalamin, though more expensive, is often selected for cases requiring neurologic support
Key Takeaway The NICE 2026 update highlights a shift from purely glycaemic control to early cardiovascular and renal protection, supporting the earlier use of SGLT2 inhibitors and GLP-1based therapies in appropriate patients
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