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Ma T, Lu W, Wang Y, Qian P, Tian H, Gao X, et al

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Once the drug is present on the skin surface, it can diffuse through the epidermis through two routes, either transepidermal(transcellular or intercellular) or transappendageal(sweat ducts, hair follicles, and pilosebaceous glands) [311]

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Metabolism of GSH Glutathione, the most plentiful thiol-containing substance of low molecular weight in cells, is a crucial antioxidant and antidote in all mammalian tissues