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(b) RNA-sequencing expression of the indicated genes
The clinical drug development program was halted in 2007 after the pivotal Phase IIb trial did not show statistically significant weight loss in the primary endpoint
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Libraries for ChIPseq were prepared at the IRB Barcelona Functional Genomics Core Facility
This means it stimulates GLP-1 receptors to reduce appetite and enhance insulin secretion, while blocking GIP signaling, which may help prevent fat storage
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