Discontinuation rates due to adverse events were reported as low and single-digit across both REDEFINE 1 and 2, which Novo Nordisk highlighted as a positive tolerability signal given the drugs dual-mechanism approach
In conclusion, this study highlights Dihexa as a novel small molecule AngIV analog that can overcome the limitations of previous peptide-based compounds
That is why tests like methylmalonic acid (4) tend to be much more accurate than serum B12 levels
Factors such as antibiotic overuse, stress, alcohol, and processed food consumption can gradually erode the gut wall, leading to conditions commonly described as "leaky gut" or increased intestinal permeability
Even simple anaemia affects many organ systems: fatigue, pallor, abdominal complaints, high heart rate, shortness of breath when climbing stairs, and dizziness
Patients who do not tolerate GLP-1 medications: those who had gastrointestinal side effects from semaglutide or tirzepatide and want to understand other options to discuss with a provider