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Physiology of Incretins (GIP and GLP-1) and Abnormalities in Type 2 Diabetes
Loss of androgen receptor promotes adipogenesis but suppresses osteogenesis in bone marrow stromal cells
Researchers are also investigating potential benefits for chronic kidney disease, liver disease (NAFLD), and even neurological conditions like Alzheimer's
We extracted GLP-1 RAs (exenatide, liraglutide, dulaglutide, lixisenatide, semaglutide, tirzepatide) and DPP-4 inhibitors (linagliptin, alogliptin, saxagliptin, sitagliptin) from Q1 2013 to Q1 2024 for all AEs classified as biliary disorders (SMQ), with the drug role selecting the primary suspect drug (PS)
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Probiotics and prebiotics have demonstrated considerable potential as adjunctive strategies by reshaping the gut microbiome, modulating immune responses, optimizing metabolic function, and mitigating oxidative stress (Figure 4)
