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17 However, among three important intracellular redox systems such as NADPH/NADP, thioredoxin red /thioredoxin ox and GSH/oxidized glutathione (GSSG), cellular GSH levels are 1000-fold higher than other redox couples

This is the most important question, and the answer depends on your specific goal

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I dont think that is clear from the research and there are a lot of different components of appetite regulation, fat storage, and base metabolic rate that come into play with obesity

However, there are multiple ways that cells can balance ROS and combat oxidative stress