In trials with patients with type 2 diabetes and overweight/obesity, after 16 weeks of treatment with Danuglipron, the high-dose (120 mg twice daily) group showed an average weight loss of 4.2 kg and a reduction in HbA1c levels by 1.2% compared to the placebo group
4,5 Role of GLP-1 Receptor Agonists for Weight Loss Neuropsychiatric considerations Emerging reports indicate potential neuropsychiatric effects of GLP-1RAs, including mood changes, appetite suppression, and cognitive function implications
Differences in nutritional status between very mild Alzheimer's disease patients and healthy controls
10.4093/dmj.2019.0185 66 GreenH.TsitsiP.MarkakiI.AarslandD.SvenningssonP
The same calorie principles apply: a 500 calorie daily deficit from your maintenance level is the evidence-backed target
Serious side effects are very rare