Al-Asmari AK, Albalawi SM, Athar MT, Khan AQ, Al-Shahrani H, Islam M
The real challenge is maintaining the health benefits for years to come
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[2] Your GP may: Refer you to psychological services if anxiety symptoms are significant, including NHS Talking Therapies for anxiety and depression Consider whether anxiety treatment should be optimised before or alongside GLP-1 therapy, following NICE guidance for anxiety disorders Coordinate care with diabetes specialists, dietitians, and mental health professionals Review the risk-benefit balance of continuing GLP-1 treatment if mental health concerns arise Screen for and manage eating disorders according to NICE guidance before initiating or continuing weight-loss treatments Remember that GLP-1 medications are not a treatment for anxiety, and any mental health benefits are likely secondary to metabolic improvements
This has resulted in development of the clinically active antiepileptic drug tiagabine which is a specific inhibitor of GAT1 (34) and more recently such studies have been focusing on development of inhibitors acting preferentially on non-GAT1 transporters (69)
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