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10.1186/s40170-020-0209-8 168 RomanoA.MartelF

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Using the GHGGHG peptide as baseline, we exchanged the first histidine residue (GXGGHG) with plausible copper coordinating side chains and a few non-plausible residues as control (Fig

This potential stems from their joint capacity to scavenge ROS, bolster the antioxidant defense system, and reduce inflammation, thereby potentially improving cardiac function and overall outcomes in sepsis, as evidenced by both pre-clinical and clinical research 5,22,23

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